{"id":32,"slug":"dermal-filler","name":"Dermal Filler","alternate_names":["필러","hyaluronic acid filler"],"aliases":[],"locale":"en","available_locales":["en"],"localized":false,"type":"product","description":"Dermal fillers are injectable gels, most commonly hyaluronic acid, used to add volume or smooth lines in the face; effects are temporary.","overview":"A dermal filler (Korean: 필러) is an injectable implant that adds volume under the skin to smooth wrinkles, folds and hollow areas in the face, lips or back of the hands. Most use cross-linked hyaluronic acid (HA). HA is gradually absorbed, so results are temporary, and it can be dissolved with hyaluronidase (an off-label use). The US FDA regulates fillers as Class III devices that need premarket approval for specific uses in adults 22 and older. It has not approved injectable silicone or body-contouring use. Korea's MFDS classifies fillers as Class 4 medical devices. The main serious risk is injection into a blood vessel, which can cause tissue necrosis, blindness or stroke. Readers should check that the product is approved for the treated area and that the injector is qualified.","official_url":null,"image_url":null,"country":null,"region":null,"wikidata_id":null,"wikipedia_url":null,"verified":false,"scores":{"authority":55,"trust":0,"citation":0},"topic":{"slug":"fat-grafting","name":"Autologous Fat Grafting"},"url":"https://worldwiki.io/entity/dermal-filler","facts":[{"id":361,"predicate":"definition","label":"Definition","value":"An injectable implant (soft tissue, lip, facial or wrinkle filler) used to make skin look smoother or fuller","unit":null,"confidence":80,"valid_from":"2023-07-06","valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[81]},{"id":362,"predicate":"regulatory_status_us","label":"US regulatory status","value":"Class III medical device that needs premarket approval (PMA); FDA product codes LMH (face) and PKY (back of hand)","unit":null,"confidence":80,"valid_from":null,"valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[303]},{"id":363,"predicate":"minimum_age_us","label":"Minimum approved age (US)","value":"22","unit":"years","confidence":80,"valid_from":"2023-07-06","valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[81]},{"id":364,"predicate":"materials","label":"Materials in FDA-approved fillers","value":"Mostly bacterial-source cross-linked hyaluronic acid; also calcium hydroxylapatite and poly-L-lactic acid","unit":null,"confidence":80,"valid_from":null,"valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[303]},{"id":365,"predicate":"recent_indications_us","label":"Newer US-approved indications","value":"Infraorbital hollowing, jawline and temple, in addition to lips, cheeks, perioral lines and nasolabial folds (approvals are product-specific)","unit":null,"confidence":80,"valid_from":null,"valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[303]},{"id":366,"predicate":"not_approved_uses_us","label":"Uses not approved by the FDA","value":"Injectable silicone for any cosmetic use; breast or buttock augmentation; needle-free injectors; over-the-counter sale","unit":null,"confidence":80,"valid_from":"2023-07-06","valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[81]},{"id":367,"predicate":"serious_risk","label":"Most serious risk","value":"Accidental injection into a blood vessel, which can cause skin necrosis, blindness or stroke; rare but possibly permanent","unit":null,"confidence":80,"valid_from":null,"valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[302]},{"id":368,"predicate":"reversal_agent","label":"Reversal agent (HA fillers only)","value":"Hyaluronidase, used off-label to break down HA nodules, excess filler and vascular complications","unit":null,"confidence":80,"valid_from":"2022-12-19","valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[304]},{"id":369,"predicate":"evidence_level","label":"Evidence for hyaluronidase in vascular occlusion","value":"No RCTs or clinical trials; evidence is limited to retrospective case series (the review itself is rated Level III)","unit":null,"confidence":80,"valid_from":"2022-12-19","valid_until":null,"verified_at":"2026-09-18 07:28:14","source_ids":[304]},{"id":60,"predicate":"duration","label":"Duration","value":"Temporary; repeat treatments needed","unit":null,"confidence":100,"valid_from":null,"valid_until":null,"verified_at":"2026-09-15 01:35:59","source_ids":[7]}],"relations":[{"type":"related_to","confidence":100,"target":{"id":25,"slug":"facial-fat-grafting","name":"Facial Fat Grafting","type":"medical","description":"Facial fat grafting transfers the patient's own fat to the face to restore volume in areas such as the cheeks, temples and under-eye region.","url":"https://worldwiki.io/entity/facial-fat-grafting"}},{"type":"related_to","confidence":100,"target":{"id":62,"slug":"stem-cell-fat-grafting","name":"Stem Cell Fat Grafting","type":"concept","description":"A consumer and marketing term used for fat grafting that is enriched with cells isolated from adipose tissue. It is not a standardised academic term and does not denote culture-expanded stem cell therapy.","url":"https://worldwiki.io/entity/stem-cell-fat-grafting"}}],"questions":[{"slug":"히알루론산-필러-지속기간은-얼마나-되나요","question":"히알루론산 필러 지속기간은 얼마나 되나요?","intent":"informational","language":"ko","short_answer":"미국 FDA는 히알루론산(HA) 필러가 몸에 흡수되며 효과가 대략 6~12개월 지속된다고 안내합니다. 칼슘하이드록실아파타이트는 약 18개월, 폴리-L-젖산은 최대 2년이고, PMMA는 흡수되지 않아 영구적입니다. 실제 지속기간은 제품, 주입 부위, 주입량, 개인의 대사 차이에 따라 달라집니다. 흡수되는 필러는 효과를 유지하려면 다시 시술해야 합니다.","url":"https://worldwiki.io/ko/q/히알루론산-필러-지속기간은-얼마나-되나요"},{"slug":"필러-부작용으로-실명이-생길-수-있나요","question":"필러 부작용으로 실명이 생길 수 있나요?","intent":"informational","language":"ko","short_answer":"드물지만 가능합니다. 필러가 혈관 안으로 들어가 눈으로 가는 동맥을 막으면 시력 상실이나 실명이 생길 수 있습니다. 2019년 메타분석에서는 혈관 합병증 93건 가운데 61%가 실명이었고, 그중 72%는 호전되지 않았습니다. 코, 미간, 이마, 팔자주름이 위험도가 높은 부위로 보고됩니다. 시술 중이나 직후 시야에 이상이 생기면 즉시 의료진에게 알려야 합니다.","url":"https://worldwiki.io/ko/q/필러-부작용으로-실명이-생길-수-있나요"},{"slug":"필러-녹이는-주사-히알루로니다아제-는-어떤-필러에-효과가-있나요","question":"필러 녹이는 주사(히알루로니다아제)는 어떤 필러에 효과가 있나요?","intent":"informational","language":"ko","short_answer":"히알루로니다아제는 히알루론산을 분해하는 효소라서 히알루론산 필러에만 효과가 있습니다. 2025년 메타분석에서 히알루론산 때문에 생긴 혈관 폐색에 이 효소를 썼을 때 부분 또는 완전 회복에 이른 비율은 84.2%였습니다. 칼슘하이드록실아파타이트, 폴리-L-젖산, PMMA처럼 히알루론산이 아닌 필러는 이 효소로 녹일 수 없습니다. 따라서 시술 전에 제품의 소재를 확인해야 합니다.","url":"https://worldwiki.io/ko/q/필러-녹이는-주사-히알루로니다아제-는-어떤-필러에-효과가-있나요"},{"slug":"가슴이나-엉덩이에-필러를-맞아도-되나요","question":"가슴이나 엉덩이에 필러를 맞아도 되나요?","intent":"informational","language":"ko","short_answer":"한국 식약처는 성형용 필러를 주로 얼굴 주름 개선과 얼굴 볼륨 개선 목적으로 허가했습니다. 가슴 확대, 엉덩이·종아리 등 몸의 볼륨 확대 목적으로 허가된 제품은 없다고 밝혔습니다. 이런 부위에 필러를 쓰는 것은 허가 범위 밖의 사용입니다. 미국 FDA도 액상 실리콘 주입은 승인하지 않았으며, 흉터와 영구적인 변형 등 심각한 부상을 일으킬 수 있다고 경고합니다.","url":"https://worldwiki.io/ko/q/가슴이나-엉덩이에-필러를-맞아도-되나요"},{"slug":"필러-시술-후-주의사항은-무엇인가요","question":"필러 시술 후 주의사항은 무엇인가요?","intent":"informational","language":"ko","short_answer":"식약처는 시술 후 술과 담배를 피하고, 시술 부위를 세게 마사지하지 말며, 찜질방이나 사우나처럼 온도가 극단적인 환경을 피하라고 안내합니다. 부작용이 생기면 바로 시술한 병원을 찾아야 합니다. 멍과 부기는 보통 며칠 안에 가라앉습니다. 다만 심한 통증, 피부색 변화, 시야 이상은 혈관 합병증의 신호일 수 있으므로 즉시 진료를 받아야 합니다.","url":"https://worldwiki.io/ko/q/필러-시술-후-주의사항은-무엇인가요"}],"sources":[{"id":7,"title":"Breast enlargement (implants)","url":"https://www.nhs.uk/tests-and-treatments/cosmetic-procedures/cosmetic-surgery/breast-enlargement/","publisher":"NHS (UK National Health Service)","type":"government","publication_date":null,"accessed_at":"2026-11-11 18:00:19"},{"id":81,"title":"Dermal Fillers (Soft Tissue Fillers)","url":"https://www.fda.gov/medical-devices/aesthetic-cosmetic-devices/dermal-fillers-soft-tissue-fillers","publisher":"U.S. Food and Drug Administration","type":"government","publication_date":"2023-07-06","accessed_at":"2026-11-11 18:01:13"},{"id":303,"title":"FDA Executive Summary: General Issues Panel Meeting on Dermal Fillers","url":"https://www.fda.gov/media/188185/download","publisher":"U.S. Food and Drug Administration","type":"government","publication_date":null,"accessed_at":"2026-11-09 18:00:42"},{"id":302,"title":"Dermal Filler Do's and Don'ts for Wrinkles, Lips and More","url":"https://www.fda.gov/consumers/consumer-updates/dermal-filler-dos-and-donts-wrinkles-lips-and-more","publisher":"U.S. Food and Drug Administration","type":"government","publication_date":null,"accessed_at":"2026-11-09 18:00:44"},{"id":304,"title":"A Scoping Review of Hyaluronidase Use in Managing the Complications of Aesthetic Interventions","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10999391/","publisher":"Aesthetic Plastic Surgery (via PubMed Central)","type":"journal","publication_date":"2022-12-19","accessed_at":"2026-11-11 18:00:08"}],"providers":[],"published_at":"2026-09-14 13:42:07","updated_at":"2026-11-12 05:20:00","verified_at":null}