{"id":23,"slug":"svf-assisted-fat-grafting","name":"SVF-assisted Fat Grafting","alternate_names":["cell-assisted lipotransfer","CAL","stem cell-enriched fat grafting","SVF 지방이식","줄기세포 지방이식"],"type":"medical","description":"SVF-assisted fat grafting (a form of cell-assisted lipotransfer) enriches the fat graft with stromal vascular fraction isolated from part of the harvested fat, with the aim of improving graft survival.","overview":"Part of the liposuctioned fat is processed into SVF, which is mixed with the remaining fat before injection. Systematic reviews of cell-assisted lipotransfer report generally higher retention than conventional grafting in pooled analyses, but study quality, cell dose and measurement methods vary, and regulatory status of SVF processing differs by country. It is not a stem cell therapy in the sense of culture-expanded cells.","official_url":null,"image_url":null,"country":null,"region":null,"wikidata_id":null,"wikipedia_url":null,"verified":false,"scores":{"authority":74,"trust":0,"citation":0},"topic":{"slug":"fat-grafting","name":"Autologous Fat Grafting"},"url":"https://worldwiki.io/entity/svf-assisted-fat-grafting","facts":[{"id":39,"predicate":"also_called","label":"Also called","value":"Cell-assisted lipotransfer (CAL)","unit":null,"confidence":100,"valid_from":null,"valid_until":null,"verified_at":"2026-09-14 13:42:07","source_ids":[23]},{"id":40,"predicate":"evidence","label":"Evidence","value":"A 2024 systematic review assessed the efficacy of cell-assisted lipotransfer; a 2021 study compared CAL with PRP-assisted lipotransfer","unit":null,"confidence":100,"valid_from":null,"valid_until":null,"verified_at":"2026-09-14 13:42:07","source_ids":[23]},{"id":41,"predicate":"mechanism","label":"Proposed mechanism","value":"Stromal cells may support angiogenesis and graft survival (hypothesis under study)","unit":null,"confidence":100,"valid_from":null,"valid_until":null,"verified_at":"2026-09-14 13:42:07","source_ids":[21]}],"relations":[{"type":"uses","confidence":100,"target":{"id":13,"slug":"stromal-vascular-fraction","name":"Stromal Vascular Fraction","type":"medical","description":"The stromal vascular fraction (SVF) is a heterogeneous mix of cells obtained from adipose tissue after removing mature fat cells; it contains stromal/stem cells, endothelial cells, pericytes and immune cells.","url":"https://worldwiki.io/entity/stromal-vascular-fraction"}},{"type":"related_to","confidence":100,"target":{"id":16,"slug":"fat-graft-survival","name":"Fat Graft Survival","type":"concept","description":"Fat graft survival (retention) is the share of transferred fat volume that remains after healing; part of every fat graft is resorbed, and reported retention varies widely by technique, site and how it is measured.","url":"https://worldwiki.io/entity/fat-graft-survival"}},{"type":"related_to","confidence":100,"target":{"id":17,"slug":"angiogenesis","name":"Angiogenesis","type":"concept","description":"Angiogenesis is the formation of new blood vessels; in fat grafting it determines whether transferred fat gains a blood supply and survives.","url":"https://worldwiki.io/entity/angiogenesis"}},{"type":"is_a","confidence":100,"target":{"id":21,"slug":"autologous-fat-grafting","name":"Autologous Fat Grafting","type":"medical","description":"Autologous fat grafting (fat transfer) is a procedure in which fat is removed from one area of the body by liposuction, processed, and injected into another area to add volume.","url":"https://worldwiki.io/entity/autologous-fat-grafting"}}],"questions":[{"slug":"what-is-stem-cell-fat-grafting","question":"What is stem cell fat grafting?","intent":"informational","language":"en","short_answer":"\"Stem cell fat grafting\" usually means cell-assisted lipotransfer: fat harvested by liposuction is enriched with stromal vascular fraction (SVF) from part of the same fat before it is injected. The added cells are intended to support blood vessel growth and graft survival. Despite the name, the graft is enriched with a mixed cell fraction, not with a purified or cultured stem cell product.","url":"https://worldwiki.io/q/what-is-stem-cell-fat-grafting"},{"slug":"conventional-vs-svf-fat-grafting","question":"What is the difference between conventional fat grafting and SVF fat grafting?","intent":"comparison","language":"en","short_answer":"Conventional fat grafting injects washed or centrifuged fat only. SVF fat grafting (cell-assisted lipotransfer) first isolates stromal vascular fraction from part of the harvested fat and mixes it into the graft. The goal is higher graft survival; systematic reviews report generally higher retention with cell assistance, but study quality and cell doses vary, and the SVF step adds processing, cost and regulatory considerations.","url":"https://worldwiki.io/q/conventional-vs-svf-fat-grafting"},{"slug":"svf-fat-grafting-in-korea-possible","question":"Can I get SVF fat grafting in Korea?","intent":"local","language":"en","short_answer":"Yes. SVF-enriched fat grafting is offered by some Korean plastic surgery clinics. In Korea, advanced regenerative medicine and cell processing are regulated by the Ministry of Health and Welfare and the Ministry of Food and Drug Safety, so ask the clinic which approvals it holds for cell processing. Foreign patients can use the Medical Korea portal to find registered institutions.","url":"https://worldwiki.io/q/svf-fat-grafting-in-korea-possible"},{"slug":"is-svf-fat-grafting-safe","question":"Is SVF fat grafting safe?","intent":"informational","language":"en","short_answer":"A 2026 literature review of autologous adipose-derived SVF in clinical use examined its safety profile across published studies. Reported adverse events are mostly those of liposuction and fat grafting themselves. Safety depends on sterile processing in a licensed facility and appropriate patient selection. Regulators warn against unapproved stem cell products, so verify the clinic's processing approvals.","url":"https://worldwiki.io/q/is-svf-fat-grafting-safe"},{"slug":"svf-치료-한국-확인사항","question":"한국에서 SVF 지방이식을 받기 전에 무엇을 확인해야 하나?","intent":"commercial","language":"ko","short_answer":"먼저 해당 의료기관이 첨단재생의료 실시기관 지정과 식약처 세포처리시설 허가를 실제로 보유하는지 확인합니다. 집도의의 전문과목과 면허, 생착률을 어떤 방법과 시점으로 측정하는지, 추가 시술이 필요할 가능성, 공여부(지방흡입 부위) 관리와 부작용 대응 계획을 묻습니다. 병원 자체 데이터와 독립적인 연구를 구분해서 근거를 요청하고, 보장이나 최상급 표현은 검증되지 않았다면 신뢰하지 않습니다.","url":"https://worldwiki.io/q/svf-치료-한국-확인사항"}],"sources":[{"id":23,"title":"Cell-Assisted Lipotransfer: A Systematic Review of its Efficacy","url":"https://pubmed.ncbi.nlm.nih.gov/37608190/","publisher":"Aesthetic Plastic Surgery (2024)","type":"academic","publication_date":"2024-01-01","accessed_at":"2026-09-14 13:42:07"},{"id":21,"title":"Advancing fat graft survival: from adipose-derived stem cell mechanisms to next-generation regenerative strategies","url":"https://pubmed.ncbi.nlm.nih.gov/42388980/","publisher":"Frontiers in Cell and Developmental Biology (2026)","type":"academic","publication_date":"2026-01-01","accessed_at":"2026-09-14 13:42:07"},{"id":24,"title":"Comparison of the Efficacy and Safety of Cell-Assisted Lipotransfer and Platelet-Rich Plasma Assisted Lipotransfer","url":"https://pubmed.ncbi.nlm.nih.gov/33845642/","publisher":"Cell Transplantation (2021)","type":"academic","publication_date":"2021-01-01","accessed_at":"2026-09-14 13:42:07"},{"id":14,"title":"ISSCR Guidelines for Stem Cell Research and Clinical Translation","url":"https://www.isscr.org/guidelines","publisher":"International Society for Stem Cell Research","type":"academic","publication_date":null,"accessed_at":"2026-09-14 13:42:07"},{"id":16,"title":"Fat Transfer Breast Augmentation","url":"https://www.plasticsurgery.org/cosmetic-procedures/fat-transfer-breast-augmentation","publisher":"American Society of Plastic Surgeons","type":"organization","publication_date":null,"accessed_at":"2026-09-14 13:42:07"}],"providers":[],"published_at":"2026-09-14 13:42:07","updated_at":"2026-09-14 22:42:07","verified_at":null}