{"id":700,"slug":"what-are-the-side-effects-of-angiogenesis-inhibitors","question":"What are the side effects of angiogenesis inhibitors?","intent":"informational","language":"en","url":"https://worldwiki.io/q/what-are-the-side-effects-of-angiogenesis-inhibitors","entity":{"slug":"angiogenesis","name":"Angiogenesis","url":"https://worldwiki.io/entity/angiogenesis"},"answer":{"short_answer":"NCI lists these common side effects of angiogenesis inhibitors: bleeding, clots in the arteries, high blood pressure, slow wound healing and protein in the urine. Drugs that target VEGF receptors can also cause fatigue, diarrhea, thyroid problems and hand-foot syndrome. Rare but serious problems include tears in the gut wall and fistulas. For bevacizumab, reported rates of high blood pressure range from 19% to 42%.","detailed_answer":"<p>For the side-effect list, see <span class=\"ref\">[1]</span>. For bevacizumab-specific rates, see <span class=\"ref\">[3]</span>. These drugs are prescribed and monitored by specialists.</p>","format":"paragraph","confidence":75,"verified_at":"2026-09-18 07:10:23","updated_at":"2026-09-18 16:10:23"},"sources":[{"id":146,"title":"Angiogenesis Inhibitors (fact sheet)","url":"https://www.cancer.gov/about-cancer/treatment/types/immunotherapy/angiogenesis-inhibitors-fact-sheet","publisher":"National Cancer Institute","type":"government","accessed_at":"2026-09-18 18:01:05"},{"id":147,"title":"Overview of Angiogenesis (in: Adair TH, Montani JP. Angiogenesis)","url":"https://www.ncbi.nlm.nih.gov/books/NBK53238/","publisher":"Morgan & Claypool Life Sciences / NCBI Bookshelf","type":"journal","accessed_at":"2026-09-18 18:01:06"},{"id":148,"title":"Bevacizumab (StatPearls)","url":"https://www.ncbi.nlm.nih.gov/books/NBK482126/","publisher":"StatPearls Publishing / NCBI Bookshelf","type":"journal","accessed_at":"2026-09-18 18:01:07"},{"id":149,"title":"Tumor Angiogenesis (editorial), Dudek AZ, Gupta K, Ramakrishnan S, Mukhopadhyay D. Journal of Oncology","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2945670/","publisher":"Journal of Oncology (Hindawi)","type":"journal","accessed_at":"2026-09-18 18:01:08"},{"id":150,"title":"Treatments for Wet AMD (Advanced Neovascular AMD)","url":"https://www.nei.nih.gov/eye-health-information/eye-conditions-and-diseases/age-related-macular-degeneration/treatments-wet-amd-advanced-neovascular-amd","publisher":"National Eye Institute (NIH)","type":"government","accessed_at":"2026-09-18 18:01:09"},{"id":151,"title":"Therapeutic Angiogenesis for Peripheral Artery Disease: Lessons Learned in Translational Science, Iyer SR, Annex BH","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5802410/","publisher":"JACC: Basic to Translational Science","type":"journal","accessed_at":"2026-09-18 18:01:10"},{"id":152,"title":"Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells, Yoshimura K et al.","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2175019/","publisher":"Aesthetic Plastic Surgery","type":"journal","accessed_at":"2026-09-18 18:01:10"},{"id":145,"title":"Adipose-Derived Stem Cell, Stromal Vascular Fraction, and Regenerative Cell Enrichment in Fat Grafting: A Systematic Review of Safety and Functional Outcomes","url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12812246/","publisher":"Cureus (PubMed Central)","type":"journal","accessed_at":"2026-09-18 18:01:04"}],"published_at":"2026-09-18 07:10:23"}