Autologous Fat
يعرف أيضا باسم: own fat, 자가지방
Autologous fat is a person's own fat tissue, harvested by liposuction and used as a natural filler or graft material in the same person.
Can your body reject your own fat after a fat transfer?
No, not in the immune sense. Autologous fat comes from the same person, so it carries no risk of immune rejection and no allergy or viral-transmission concerns. Some of the graft is still usually lost, because transferred fat has no blood supply at first and fat cells far from nearby tissue can die before new vessels form. Reviews report resorption of 25% to 80%, depending on technique and the recipient site.
حقائق أساسية
| المحمول | القيمة | المصدر |
|---|---|---|
| First reported fat graft | 1893, Gustav Neuber moved fat from the arm to the orbital region to correct scarring | [2]organizationFat grafting history and applicationsAmerican Society of Plastic Surgeons |
| Standardized technique | Structural fat grafting (harvest, refinement, placement), published by Sydney Coleman in the 1990s | [2]organizationFat grafting history and applicationsAmerican Society of Plastic Surgeons |
| Common donor sites | Abdomen and thighs, harvested with a syringe or cannula after tumescent infiltration | [3]organization지방이식 (Fat transplantation) — N의학정보서울대학교병원 |
| Processing and placement | Decanting and/or centrifugation to separate viable fat, then injection in small droplets for blood supply | [2]organizationFat grafting history and applicationsAmerican Society of Plastic Surgeons |
| Typical uses | Facial volume loss, post-surgical or post-traumatic depressions, hemifacial atrophy, Romberg disease, lipodystrophy, breast, buttocks, hands | [3]organization지방이식 (Fat transplantation) — N의학정보서울대학교병원 |
| Reported volume retention (temple grafting) | 33–65% across 8 studies (719 patients); 46.4% with fat only vs 64.8% SVF-assisted %حتى تاريخ 20 سبتمبر 2024 | [4]journalAutologous fat grafting for cosmetic temporal augmentation: a systematic review (Nasim S et al., Front Surg 2024;11:1410162)Frontiers in Surgery (via PubMed Central) |
| Evidence level (temple grafting) | 7 of 8 included studies were retrospective; most used subjective photo-based assessment; the authors call for RCTs with objective imagingحتى تاريخ 20 سبتمبر 2024 | [4]journalAutologous fat grafting for cosmetic temporal augmentation: a systematic review (Nasim S et al., Front Surg 2024;11:1410162)Frontiers in Surgery (via PubMed Central) |
| US regulatory status | Exempt from 21 CFR Part 1271 when removed and re-implanted in the same person during the same surgical procedure (§1271.15(b)) | [5]academic21 CFR § 1271.15 – Are there any exceptions from the requirements of this part?Legal Information Institute, Cornell Law School (reproducing the US Code of Federal Regulations) |
| FDA guidance on exception scope | CBER final guidance, 'Same Surgical Procedure Exception under 21 CFR 1271.15(b): Questions and Answers', issued November 2017حتى تاريخ 1 نوفمبر 2017 | [6]governmentSame Surgical Procedure Exception under 21 CFR 1271.15(b): Questions and Answers Regarding the Scope of the ExceptionUS Food and Drug Administration (CBER) |
| Known risks | Partial resorption needing repeat grafting; lumps, necrosis or fibrosis with large volumes; rare fat embolism with skin necrosis, blindness or stroke | [3]organization지방이식 (Fat transplantation) — N의학정보서울대학교병원 |
| Gluteal grafting safety recommendation | Inject only into the subcutaneous space above the gluteal fascia; the societies support mandates for real-time ultrasound guidanceحتى تاريخ 18 أغسطس 2022 | [7]organizationGluteal Fat Grafting: A joint safety statementAmerican Society of Plastic Surgeons / The Aesthetic Society / PSF / ASERF |
| Autologous (NCI) | Taken from an individual's own tissues, cells or DNA | [1]governmentNCI Dictionary of Cancer Terms: autologousNational Cancer Institute (NCI) |
نظرة عامة
Autologous fat is fat tissue taken from a person's own body, usually by liposuction from the abdomen or thighs, and put back into the same person. After harvesting, the fat is usually decanted or centrifuged to remove fluid and debris. It is then injected in small amounts so that each deposit can pick up a blood supply. Uses include restoring lost facial volume, treating scars and contour defects, breast reconstruction and buttock augmentation. The immune system is not expected to reject the tissue, but some of the graft is absorbed. How much survives varies widely between reviews and depends on how it is measured. In the US, tissue that is removed and put back during the same surgical procedure is exempt from 21 CFR Part 1271 under §1271.15(b). Readers should check the retention evidence behind any technique and the risks, including fat embolism, which has caused deaths after gluteal fat grafting.
مزودون موثقون
القوائم المدفوعة موسومة بوضوح. التحقق مستقل عن الدفع.SC301의원
SC301의원 (SC301 Clinic) is a plastic surgery clinic in Gangnam, Seoul, South Korea whose official site presents SVF (stromal vascular fraction) fat grafting for the breast and face, liposuction, lifting and cell banking as its main services.
عرض المزودالمراجع
نسبة المصادر المستقلة 100% (7/7)- المستوى A · governmentNCI Dictionary of Cancer Terms: autologous — National Cancer Institute (NCI) · تاريخ الاطلاع 12 نوفمبر 2026 · صفحة الدليل
- المستوى C · organizationFat grafting history and applications — American Society of Plastic Surgeons · تاريخ الاطلاع 11 نوفمبر 2026 · صفحة الدليل
- المستوى C · organization지방이식 (Fat transplantation) — N의학정보 — 서울대학교병원 · تاريخ الاطلاع 12 نوفمبر 2026 · صفحة الدليل
- المستوى B · journalAutologous fat grafting for cosmetic temporal augmentation: a systematic review (Nasim S et al., Front Surg 2024;11:1410162) — Frontiers in Surgery (via PubMed Central) · تاريخ الاطلاع 11 نوفمبر 2026 · صفحة الدليل
- المستوى B · academic21 CFR § 1271.15 – Are there any exceptions from the requirements of this part? — Legal Information Institute, Cornell Law School (reproducing the US Code of Federal Regulations) · تاريخ الاطلاع 11 نوفمبر 2026 · صفحة الدليل
- المستوى A · governmentSame Surgical Procedure Exception under 21 CFR 1271.15(b): Questions and Answers Regarding the Scope of the Exception — US Food and Drug Administration (CBER) · تاريخ الاطلاع 12 نوفمبر 2026 · صفحة الدليل
- المستوى C · organizationGluteal Fat Grafting: A joint safety statement — American Society of Plastic Surgeons / The Aesthetic Society / PSF / ASERF · تاريخ الاطلاع 11 نوفمبر 2026 · صفحة الدليل