academicEvidence level BIndependent

Evidence page

Large-Volume Fat Grafting: Identifying Risk Factors for Fat Necrosis (Chang CS, … ; Plast Reconstr Surg 2022;150(5):941e-949e)

Plastic and Reconstructive Surgery

accessed Nov 12, 2026Updated Nov 12, 2026

Original source

https://pubmed.ncbi.nlm.nih.gov/35993869/

pubmed.ncbi.nlm.nih.gov

Verification

Verification	Independent of the subject
Evidence level	B · Peer-reviewed or professional body
Independent	Independent of the subject
Source	academic
Link status	Reachable at last check

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Cited by (1)

Answer한 번에 300cc 이상 넣는 대용량 가슴 지방이식은 가능한가요? 조건과 위험은 무엇인가요?“A retrospective review was performed on 83 consecutive patients who underwent large-volume fat grafting (>100 cc) to the breast … A total of 148 breasts underwent 170 autologous fat transplantations. … median graft volume was 300 cc … Overall incidence of necrosis was 32.9 percent, with 47.8 percent in previously irradiated patients. Increased incidence of necrosis was associated with increasing fat graft volumes (OR, 1.002; p = 0.032), increasing body mass index (OR, 1.13; p = 0.04), and simultaneous implant exchange with fat ( p = 0.003). Fat grafting volumes greater than 450 cc in a single breast were also associated with an increase in fat necrosis ( p = 0.04).”