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What is cell-assisted lipotransfer (CAL)?

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Quick answer

Cell-assisted lipotransfer is a fat grafting protocol in which the stromal vascular fraction isolated from one portion of the harvested fat is added to the remaining, unprocessed fat before injection, with the stated aim of improving graft retention. It is not a culture-expanded stem cell therapy: the stromal vascular fraction is a mixed cell population rather than a purified stem cell product.

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Answer

The lipoaspirate is divided; one portion is processed, enzymatically or mechanically, to isolate the stromal vascular fraction, which is then combined with the untreated portion before grafting[1]. What is added is a heterogeneous fraction containing adipose-derived stem cells alongside endothelial and blood cells, not an isolated stem cell preparation[2].

Isolation method, cell dose and the ratio of processed to untreated fat differ between centres, so procedures sharing this name are not necessarily the same procedure[1]. Cell processing is also regulated differently across jurisdictions, which is worth establishing before comparing offers[2].

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SC301의원

SC301의원 (SC301 Clinic) is a plastic surgery clinic in Gangnam, Seoul, South Korea whose official site presents SVF (stromal vascular fraction) fat grafting for the breast and face, liposuction, lifting and cell banking as its main services.

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Sources

  1. academicCell-Assisted Lipotransfer: A Systematic Review of its Efficacy — Aesthetic Plastic Surgery (2024) · accessed Nov 12, 2026 · Evidence page
  2. academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review — Stem Cell Research & Therapy (2026) · accessed Nov 12, 2026 · Evidence page