Stromal Vascular Fraction
Also known as: SVF, adipose SVF, 기질혈관분획, SVF 세포
The stromal vascular fraction (SVF) is a heterogeneous mix of cells obtained from adipose tissue after removing mature fat cells; it contains stromal/stem cells, endothelial cells, pericytes and immune cells.
What is SVF (stromal vascular fraction)?
Stromal vascular fraction (SVF) is the heterogeneous mix of cells left after mature fat cells are removed from processed adipose tissue. It contains stromal/stem cells, endothelial cells, pericytes and immune cells. SVF is isolated from liposuctioned fat by enzymatic or mechanical processing and is used in research and in some fat grafting procedures. It is not a purified stem cell product, and its composition depends on the processing method.
Key facts
| Predicate | Value | Source |
|---|---|---|
| Source tissue | Adipose (fat) tissue obtained by liposuction | [1] |
| Composition | Heterogeneous: stromal/stem cells, endothelial cells, pericytes, immune cells, fibroblasts (mature adipocytes removed) | [1] |
| Processing | Enzymatic digestion or mechanical/ultrasonic processing; the ISSCR notes such processing can alter the original function of the cells | [2] |
| Culture expansion | No — SVF is freshly isolated, not expanded in culture (unlike ADSC) | [1] |
| Regulatory note | Regulatory status depends on processing and use; the US FDA has warned consumers about unapproved stem cell products | [3] |
Overview
SVF is produced from liposuctioned fat by enzymatic digestion or mechanical processing and then separated from adipocytes. It is not a purified stem cell product: stem/stromal cells are a minority of the cells. SVF is used in research and in some aesthetic and regenerative procedures, including cell-assisted fat grafting. The composition and clinical value of SVF depend on the processing method and the indication, and regulatory status varies by country. The ISSCR notes that enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells, so safety and efficacy must be shown for each specific use.
Verified providers
Sponsored listings are labeled. Verification is independent of payment.SC301의원
SC301의원 (SC301 Clinic) is a plastic surgery clinic in Gangnam, Seoul, South Korea whose official site presents SVF (stromal vascular fraction) fat grafting for the breast and face, liposuction, lifting and cell banking as its main services.
View providerEvidence & claims
Official claims are statements by the provider; they are not verified by worldwiki unless marked otherwise.| Claim | Type | Evidence | Source |
|---|---|---|---|
| SVF is a heterogeneous cell population, not a purified stem cell product. | definition | high | Safety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review |
| Enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells; safety and efficacy must be shown for each use. | regulatory | high | ISSCR Guidelines for Stem Cell Research and Clinical Translation |
References
Independent source ratio 100% (3/3)- Level B · academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review — Stem Cell Research & Therapy (2026) · accessed 2026-09-14
- Level B · academicISSCR Guidelines for Stem Cell Research and Clinical Translation — International Society for Stem Cell Research · accessed 2026-09-14
- Level A · governmentFDA Warns About Stem Cell Therapies — U.S. Food and Drug Administration · accessed 2026-09-14