What is the difference between white fat and brown fat?
White fat cells hold one large lipid droplet, which fills about 90% of the cell, and mainly store energy as triglycerides. Brown fat cells hold many small droplets and many mitochondria. They use uncoupling protein 1 (UCP1) to burn energy as heat without shivering. In adults, brown fat is found mainly in the neck, above the collarbones, along the spine and in the centre of the chest. White fat is found under the skin and around the organs.
Answer
A third type, beige fat, forms inside white fat depots after cold exposure or similar stimuli and can also produce heat [2]. Studies from 2009 found brown fat more often after cold exposure and less often in older people and people with a higher BMI [5].
Stem cells in cosmetic surgery
In cosmetic surgery, "stem cell" procedures almost always use adipose-derived stem cells. The stromal vascular fraction (SVF), which contains them, is separated from liposuctioned fat and mixed into the fat being grafted, as in stem cell breast augmentation and stem cell fat grafting.
Sources
- journalComparative anatomy and metabolic profiles of brown and white adipose tissue in humans — Frontiers in Endocrinology · accessed Nov 10, 2026 · Evidence page
- journalPlasticity of Adipose Tissues: Interconversion among White, Brown, and Beige Fat and Its Role in Energy Homeostasis — Biomolecules (MDPI), via PubMed Central · accessed Nov 10, 2026 · Evidence page
- organizationAdipose Tissue (Body Fat): Anatomy & Function — Cleveland Clinic · accessed Nov 10, 2026 · Evidence page
- organizationVisceral Fat: What It Is & How It Affects You — Cleveland Clinic · accessed Nov 10, 2026 · Evidence page
- journalBrown adipose tissue: what have we learned since its recent identification in human adults — Arquivos Brasileiros de Endocrinologia & Metabologia · accessed Nov 10, 2026 · Evidence page
- journalLeptin 30 years – A chat with Jeffrey M. Friedman — Archives of Endocrinology and Metabolism, via PubMed Central · accessed Nov 10, 2026 · Evidence page
- journalLipodystrophies - StatPearls — NCBI Bookshelf, U.S. National Library of Medicine · accessed Nov 10, 2026 · Evidence page
- governmentObesity and overweight (fact sheet) — World Health Organization · accessed Nov 10, 2026 · Evidence page
- journalA Simple and Effective Mechanical Method for Adipose-Derived Stromal Vascular Fraction Isolation — Cureus, via PubMed Central · accessed Nov 10, 2026 · Evidence page
- governmentImportant Patient and Consumer Information About Regenerative Medicine Therapies — U.S. Food and Drug Administration · accessed Nov 10, 2026 · Evidence page