Cryopreservation
Also known as: 세포 동결보존, 냉동보존, cryobanking
Cryopreservation is cooling and storing cells, tissues or organs at very low or freezing temperatures so they can be used later.
Can SVF be frozen and stored (cryopreserved)?
Yes. SVF can be cryopreserved in liquid nitrogen with cryoprotectants. Freezing and thawing reduce the number of living cells; a 2019 study reported lower cell counts after cryopreservation but preserved stem cell potency in surviving cells, and a 2026 systematic review examined viability effects across studies. Viability after thaw should be measured before clinical use.
Key facts
| Predicate | Value | Source |
|---|---|---|
| Definition (NCI) | Cooling and storing cells, tissues or organs at very low or freezing temperatures to save them for future use | [1] |
| Effect on SVF (study title finding) | A 2019 study reported that cryopreservation reduces SVF cell counts but not the stem cell potency of surviving cells | [2] |
| Systematic review | A 2026 systematic review examined effects of cryopreservation on SVF viability in human adipose tissue | [3] |
Overview
Cells are usually stored in liquid nitrogen (about −196 °C) with cryoprotectants. Freezing and thawing reduce the number of surviving cells; published studies on adipose SVF report reduced cell counts after cryopreservation while stem cell potency of surviving cells may be retained. Storage conditions, documentation and consent are regulated in most countries.
Evidence & claims
Official claims are statements by the provider; they are not verified by worldwiki unless marked otherwise.| Claim | Type | Evidence | Source |
|---|---|---|---|
| Cryopreservation reduces SVF cell counts but surviving cells retain stem cell potency. Single study; see 2026 systematic review for broader picture. | outcome | limited | Cryopreservation of Stromal Vascular Fraction Cells Reduces Their Counts but Not Their Stem Cell Potency |
References
Independent source ratio 100% (5/5)- Level A · governmentNCI Dictionary of Cancer Terms: cryopreservation — National Cancer Institute (NCI) · accessed 2026-09-14
- Level B · academicCryopreservation of Stromal Vascular Fraction Cells Reduces Their Counts but Not Their Stem Cell Potency — Plastic and Reconstructive Surgery – Global Open (2019) · accessed 2026-09-14
- Level B · academicEffects of Cryopreservation on Stromal Vascular Fraction Viability in Human Adipose Tissue: Insights from a Systematic Review — Tissue Engineering and Regenerative Medicine (2026) · accessed 2026-09-14
- Level B · organizationAbout Stem Cells — patient resource — International Society for Stem Cell Research · accessed 2026-09-14
- Level B · academicISSCR Guidelines for Stem Cell Research and Clinical Translation — International Society for Stem Cell Research · accessed 2026-09-14