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医疗 · Stem Cell

Stromal Vascular Fraction

别名: 脂肪来源基质血管组分, 自体脂肪基质血管组分, SVF细胞, 基质血管细胞组分, 血管基质成分, 血管基质片段, SVF

发布 2026年9月14日更新 2026年11月11日
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定义

The stromal vascular fraction (SVF) is a heterogeneous mix of cells obtained from adipose tissue after removing mature fat cells; it contains stromal/stem cells, endothelial cells, pericytes and immune cells.

快速回答

What is SVF (stromal vascular fraction)?

Stromal vascular fraction (SVF) is the heterogeneous mix of cells left after mature fat cells are removed from processed adipose tissue. It contains stromal/stem cells, endothelial cells, pericytes and immune cells. SVF is isolated from liposuctioned fat by enzymatic or mechanical processing and is used in research and in some fat grafting procedures. It is not a purified stem cell product, and its composition depends on the processing method.

已验证 2026年9月15日

关键事实

属性值来源
Source tissueAdipose (fat) tissue obtained by liposuction[1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026)
CompositionHeterogeneous: stromal/stem cells, endothelial cells, pericytes, immune cells, fibroblasts (mature adipocytes removed)[1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026)
ProcessingEnzymatic digestion or mechanical/ultrasonic processing; the ISSCR notes such processing can alter the original function of the cells[2]organizationISSCR Guidelines for Stem Cell Research and Clinical TranslationInternational Society for Stem Cell Research
Culture expansionNo — SVF is freshly isolated, not expanded in culture (unlike ADSC)[1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026)
Regulatory noteRegulatory status depends on processing and use; the US FDA has warned consumers about unapproved stem cell products[3]governmentFDA Warns About Stem Cell TherapiesU.S. Food and Drug Administration

概述

SVF is produced from liposuctioned fat by enzymatic digestion or mechanical processing and then separated from adipocytes. It is not a purified stem cell product: stem/stromal cells are a minority of the cells. SVF is used in research and in some aesthetic and regenerative procedures, including cell-assisted fat grafting. The composition and clinical value of SVF depend on the processing method and the indication, and regulatory status varies by country. The ISSCR notes that enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells, so safety and efficacy must be shown for each specific use.

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SC301의원

SC301의원 (SC301 Clinic) is a plastic surgery clinic in Gangnam, Seoul, South Korea whose official site presents SVF (stromal vascular fraction) fat grafting for the breast and face, liposuction, lifting and cell banking as its main services.

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证据与声明

官方声明是服务方的陈述,除非另有标注,否则未经 worldwiki 验证。
主张类型证据来源
SVF is a heterogeneous cell population, not a purified stem cell product.definition高Safety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review
Enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells; safety and efficacy must be shown for each use.regulatory有限ISSCR Guidelines for Stem Cell Research and Clinical Translation

参考来源

独立来源比例 80% (4/5)
等级 A · 2等级 B · 1等级 C · 1
  1. 等级 B · academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review — Stem Cell Research & Therapy (2026) · 访问于 2026年11月12日 · 证据页
  2. 等级 C · organizationISSCR Guidelines for Stem Cell Research and Clinical Translation — International Society for Stem Cell Research · 访问于 2026年11月12日 · 证据页
  3. 等级 A · governmentFDA Warns About Stem Cell Therapies — U.S. Food and Drug Administration · 访问于 2026年9月15日 · 证据页
  4. 等级 A · government再生・細胞医療・遺伝子治療について（再生医療等安全性確保法・再生医療等提供計画・認定再生医療等委員会） — 厚生労働省 · 访问于 2026年11月12日 · 证据页
  5. organization幹細胞を用いた自由診療についての日本再生医療学会からの声明 — 一般社団法人 日本再生医療学会 · 访问于 2026年11月12日 · 证据页
变更历史
首次发布 · 2026年9月14日