Stromal Vascular Fraction
别名: 脂肪来源基质血管组分, 自体脂肪基质血管组分, SVF细胞, 基质血管细胞组分, 血管基质成分, 血管基质片段, SVF
The stromal vascular fraction (SVF) is a heterogeneous mix of cells obtained from adipose tissue after removing mature fat cells; it contains stromal/stem cells, endothelial cells, pericytes and immune cells.
What is SVF (stromal vascular fraction)?
Stromal vascular fraction (SVF) is the heterogeneous mix of cells left after mature fat cells are removed from processed adipose tissue. It contains stromal/stem cells, endothelial cells, pericytes and immune cells. SVF is isolated from liposuctioned fat by enzymatic or mechanical processing and is used in research and in some fat grafting procedures. It is not a purified stem cell product, and its composition depends on the processing method.
关键事实
| 属性 | 值 | 来源 |
|---|---|---|
| Source tissue | Adipose (fat) tissue obtained by liposuction | [1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026) |
| Composition | Heterogeneous: stromal/stem cells, endothelial cells, pericytes, immune cells, fibroblasts (mature adipocytes removed) | [1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026) |
| Processing | Enzymatic digestion or mechanical/ultrasonic processing; the ISSCR notes such processing can alter the original function of the cells | [2]organizationISSCR Guidelines for Stem Cell Research and Clinical TranslationInternational Society for Stem Cell Research |
| Culture expansion | No — SVF is freshly isolated, not expanded in culture (unlike ADSC) | [1]academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature reviewStem Cell Research & Therapy (2026) |
| Regulatory note | Regulatory status depends on processing and use; the US FDA has warned consumers about unapproved stem cell products | [3]governmentFDA Warns About Stem Cell TherapiesU.S. Food and Drug Administration |
概述
SVF is produced from liposuctioned fat by enzymatic digestion or mechanical processing and then separated from adipocytes. It is not a purified stem cell product: stem/stromal cells are a minority of the cells. SVF is used in research and in some aesthetic and regenerative procedures, including cell-assisted fat grafting. The composition and clinical value of SVF depend on the processing method and the indication, and regulatory status varies by country. The ISSCR notes that enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells, so safety and efficacy must be shown for each specific use.
已验证服务机构
付费展示均有标注。验证与付费无关。SC301의원
SC301의원 (SC301 Clinic) is a plastic surgery clinic in Gangnam, Seoul, South Korea whose official site presents SVF (stromal vascular fraction) fat grafting for the breast and face, liposuction, lifting and cell banking as its main services.
查看机构证据与声明
官方声明是服务方的陈述,除非另有标注,否则未经 worldwiki 验证。| 主张 | 类型 | 证据 | 来源 |
|---|---|---|---|
| SVF is a heterogeneous cell population, not a purified stem cell product. | definition | 高 | Safety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review |
| Enzymatic or ultrasonic processing of adipose tissue can alter the original function of the cells; safety and efficacy must be shown for each use. | regulatory | 有限 | ISSCR Guidelines for Stem Cell Research and Clinical Translation |
参考来源
独立来源比例 100% (3/3)- 等级 B · academicSafety profile of autologous adipose-derived stromal vascular fraction in clinical use: an exhaustive literature review — Stem Cell Research & Therapy (2026) · 访问于 2026年9月20日 · 证据页
- 等级 C · organizationISSCR Guidelines for Stem Cell Research and Clinical Translation — International Society for Stem Cell Research · 访问于 2026年9月20日 · 证据页
- 等级 A · governmentFDA Warns About Stem Cell Therapies — U.S. Food and Drug Administration · 访问于 2026年9月15日 · 证据页